A Genomic Analysis of Community-Associated C. Difficile Infection Demonstrates Integration With National and International Strain Clusters and Limited Direct Transmission.

Dumyati, Ghinwa; Pecora, Nicole D; Holt, Kathleen; Taffner, Samantha; Tesini, Brenda

doi:10.1093/infdis/jiag176

A Genomic Analysis of Community-Associated C. Difficile Infection Demonstrates Integration With National and International Strain Clusters and Limited Direct Transmission.

2026-03-30, The Journal of Infectious Diseases (10.1093/infdis/jiag176) (online)
Ghinwa Dumyati, Nicole D Pecora, Kathleen Holt, Samantha Taffner, and Brenda Tesini (?)

Clostridioides difficile is a life-threatening gastrointestinal infection. Once predominantly associated with healthcare exposure, community-associated C. difficile infections (CA-CDI) now account for more than half of U.S. cases, and sources and transmission dynamics remain poorly defined.

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A Genomic Analysis of Community-Associated C. Difficile Infection Demonstrates Integration With National and International Strain Clusters and Limited Direct Transmission.