Differential IgG responses to PfHRP2 across the malaria severity spectrum.
2026-06-08, Transactions of the Royal Society of Tropical Medicine and Hygiene (10.1093/trstmh/trag034) (online)Praveen Kumar Bharti, Sneha Bhandari, Sri Krishna, Anil K Verma, Ritesh Ranjha, and Himanshu Gupta (?)
Severe malaria represent a leading cause of mortality in Plasmodium falciparum infections. Sequestered parasites release PfHRP2, which increases at schizont rupture. Thus, this study explored Pfhrp2 gene copy number variation and immune (IgG) response in mild (MM), severe (SM) and cerebral malaria (CM) cases.
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