Setdb1 represses anti-tumor immunity and tertiary lymphoid structures in hepatocellular carcinoma.
2026-07-16, Journal of hepatology (10.1016/j.jhep.2026.07.007)Si-Jia Shen, Ke Zhou, Chen-Yu Wang, Huan Li, Zhou Ye, Xi-Wei Wang, Zi-Qi Mu, Chuang Wang, Jia Shi, Ze-Yu Tang, Hong-Bing Shu, Jingping Yuan, Ming-Kai Chen, Lian-Yun Li, and Min Wu (?)
Tertiary lymphoid structures (TLSs) are ectopic lymphoid structures in chronic inflammation or tumors in peripheral tissues. TLS maturation is associated with clinical advantages of tumor immunotherapy. However, the underlying mechanisms of TLS formation remain elusive. Here we investigated the roles of SETDB1 in TLS formation in hepatocellular carcinoma (HCC).
This article has not yet been included in any curations.
Comments
There are no comments on this article yet.
You need to login or register to comment.