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Preoperative Stereotactic Radiotherapy for Spinal Metastases: Study Protocol for a Prospective Exploratory Interventional Trial.

2026-11-12, Neurosurgery practice (10.1227/neuprac.0000000000000316) (online)
Carla Marie Zwerenz, Thomas Asendorf, Bilal Younes, Torge Huckhagel, Lucas Weiser, Wolfgang Lehmann, Stefan Rieken, Jan Tobias Oelmann, Andrea Hille, Leif Hendrik Dröge, Stephanie Bendrich, Manuel Guhlich, Sandra Donath, Laura Anna Fischer, Daniela Schmitt, Veit Rohde, Rami El Shafie, and Tammam Abboud (?)
Spinal metastases frequently require surgical stabilization and/or decompression followed by postoperative radiotherapy (RT). Preoperative stereotactic body radiotherapy (SBRT) may reduce postoperative complications and improve local tumor control. The primary objective of this exploratory trial is to evaluate safety and preliminary efficacy of preoperative SBRT in patients with spinal metastases.
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